Skip to main content

Next TB Vaccine Candidates.

Next TB Vaccine Candidates.

Next TB Vaccine Candidates.


Pharma Fix: The quest for the next tuberculosis vaccine

Tuberculosis (TB) is a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. It primarily affects the lungs but can also affect other parts of the body. TB is a major global health problem, with an estimated 10 million cases and 1.4 million deaths in 2019, according to the World Health Organization (WHO).

The current TB vaccine, Bacille Calmette-Guérin (BCG), has been in use since 1921 and is the only vaccine currently available to prevent TB. However, BCG has limitations in its effectiveness, particularly against the most common form of TB in adults. As a result, there is a need for a new TB vaccine that can provide better protection against the disease.

There are currently several TB vaccine candidates in various stages of development. One promising candidate is the M72/AS01E vaccine, which has shown efficacy in a Phase IIb trial conducted in South Africa. The trial showed that the vaccine reduced the incidence of TB disease by 50% in HIV-negative adults with latent TB infection.

Another candidate is the H56:IC31 vaccine, which has shown promising results in preclinical studies and a Phase IIa trial in South Africa. The vaccine is currently undergoing Phase IIb trials in several countries.

Other TB vaccine candidates in development include a DNA vaccine, a viral vector vaccine, and a protein subunit vaccine. These candidates are still in the early stages of development and require further testing to determine their safety and efficacy.

Developing a new TB vaccine is a challenging task, as the bacterium that causes TB is particularly difficult to target. However, advances in vaccine technology and increased investment in TB vaccine research offer hope for the development of a more effective TB vaccine in the future.

.





Comments

Popular posts from this blog

Introducing My Shocks. 😉 Ciggerate Whatsapp Status (SAD BOYS)#short #shorts #cigarette

via https://youtu.be/RpDENmVEg7M

MC STAN-Gender (official video) Insaan 2023 (Slowed+reverb) New Song #viral #short #shorts

via https://youtu.be/V8wetb-ri5s

H. Welton Flynn: A Pioneer in Public Service

H. Welton Flynn: A Pioneer in Public Service By Jeremy Menzies This February for Black History Month we're highlighting one of San Francisco's most important figures in transportation, H. Welton Flynn. Flynn is best known for his key leadership at the SF Public Utilities Commission and as the inaugural chairman of the SFMTA Board of Directors. Mr. Flynn was the first African American appointed to a city commission and served the longest term of any commissioner in San Francisco’s history. He served under six different mayors, being elected to the office of President or Chairman more than a dozen times. Welton Flynn in 1978 during the inaugural run of Muni light rail in the Market Street Subway. Flynn’s leadership on the Public Utilities Commission was crucial during this era of change and adoption of new technology in San Francisco transit. Flynn's long tenure in transit began with his appointment to the Public Utilities Commission, which oversaw Muni operations, in 19...